- URL: https://oncogenomics.bmc.lu.se/MutationExplorer
- Source code: https://github.com/cbrueffer/MutationExplorer (2-clause BSD license)
To facilitate research cancer datasets these days get ever larger. Within the Sweden Cancerome Analysis Network–Breast thousands of breast tumors have already undergone RNA sequencing, and the number grows daily. In a recent research project we demonstrated that this data can be used to call somatic mutations, which can e.g. help guide patient treatment or be used as targets for detecting circulating tumor DNA in patient blood samples.
As part of this project we provide the web portal SCAN-B Mutationexplorer to enable the exploration of mutations from 3,217 primary breast tumor transcriptomes. The underlying software, MutationExplorer, is freely available on GitHub and can be adapted to other datasets.